Gallium triflate for catalysis

Triflate ion model

Since the synthesis of trifluoromethanesulfonic acid or triflic acid by Robert N. Hazeldine, researchers have synthesized and used many metal triflates as catalysts. Because many organic chemistry reactions are based on Lewis acids catalysis, a family to which metal triflates belong.

Today, the chemical industry tends to become eco-responsible by setting up less energy consuming processes using less polluting products. Gallium (III) triflate has interesting properties for this “Green Chemistry”, due to its stability and water solubility, which thus opens the way to organic synthesis in aqueous medium. It has also demonstrated good catalytic activity, allowing the reactions to be carried out in so-called “soft” conditions.


■ “Gallium (III) Triflate: an efficient and a sustainable Lewis acid catalyst for organic synthetic transformations”, Prakash et al., JACS 2011